Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745937 | 0.81 | SMYD3 (0.44) | P2RY12 | |
| SCHEMBL25438364 | 0.80 | MTOR (0.48) | — | |
| SCHEMBL30745941 | 0.76 | P2RY12 (0.39) | P2RY12ADORA1ADORA3 | |
| SCHEMBL30613802 | 0.72 | CA1 (0.40) | CNR2 | |
| SCHEMBL3118565 | 0.71 | MTHFD2 (0.50) | — | |
| SCHEMBL3119582 | 0.70 | PDE10A (0.54) | — | |
| SCHEMBL12811458 | 0.69 | LMNA (0.40) | CNR2 | |
| SCHEMBL22440456 | 0.68 | LMNA (0.40) | CNR2 | |
| SCHEMBL13261239 | 0.68 | NAMPT (0.55) | — | |
| SCHEMBL14144348 | 0.66 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472636-A2 | TETRAHYDROPYRIDOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023150619-A2 | TETRAHYDROPYRIDOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-08-10 | — | — | WO | disclosed |