Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259627 | 1.00 | NOTUM (1.00) | NOTUMHTR2AHTR2CALDH1A1TSHR | |
| SCHEMBL7278393 | 0.89 | NOTUM (0.80) | NOTUMHTR2AHTR2CALDH1A1TSHR | |
| SCHEMBL9844700 | 0.77 | NOTUM (0.62) | NOTUMHTR2AHTR2CDAO | |
| SCHEMBL9259282 | 0.77 | NOTUM (0.62) | NOTUMALDH1A1TSHRDAOKDM4E | |
| SCHEMBL946355 | 0.77 | NOTUM (0.62) | NOTUMALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL9735956 | 0.77 | NOTUM (0.62) | NOTUMHTR2AHTR2CALDH1A1DAO | |
| SCHEMBL7379739 | 0.77 | NOTUM (0.62) | NOTUMHTR2AHTR2CALDH1A1TSHR | |
| SCHEMBL9844702 | 0.77 | NOTUM (0.62) | NOTUMALDH1A1TSHRDAOKDM4E | |
| SCHEMBL9736815 | 0.75 | NOTUM (0.56) | NOTUMALDH1A1TSHR | |
| SCHEMBL235219 | 0.74 | NOTUM (0.59) | NOTUMHTR2AHTR2CHTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925069-B | Synthesis method of iron-catalyzed fused ring [1,2-a ] indole compound | 湖北工程学院 | 2025-03-28 | — | — | CN | disclosed |
| CN-116925069-A | Synthesis method of iron-catalyzed fused ring [1,2-a ] indole compound | 湖北工程学院 | 2023-10-24 | — | — | CN | disclosed |