Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21463329 | 1.00 | DAO (0.51) | DAOHSP90AA1TNKS2TNKSHCAR1 | |
| SCHEMBL30615576 | 0.89 | TGFBR1 (0.47) | DAOHSP90AA1TNKS2TNKSHCAR1 | |
| SCHEMBL30615475 | 0.83 | HSP90AA1 (0.56) | DAOHSP90AA1TNKS2HCAR1KDM4E | |
| SCHEMBL30615399 | 0.81 | DAO (0.47) | DAOHSP90AA1TNKSFEN1 | |
| SCHEMBL30615328 | 0.78 | ACHE (0.44) | DAOHSP90AA1TNKSKDM4EALDH1A1 | |
| SCHEMBL1699090 | 0.77 | DAO (0.62) | DAOTNKS2TNKSALDH1A1HTT | |
| SCHEMBL8885299 | 0.77 | AURKA (0.58) | DAOHSP90AA1KDM4EALDH1A1HTT | |
| SCHEMBL21467334 | 0.75 | DAO (0.53) | DAOHSP90AA1HCAR1ALDH1A1FEN1 | |
| SCHEMBL30615518 | 0.75 | DAO (0.53) | DAOHSP90AA1HCAR1ALDH1A1FEN1 | |
| SCHEMBL21463892 | 0.72 | GABRP (0.55) | DAOHSP90AA1TNKS2HCAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |