Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467314 | 1.00 | L3MBTL1 (0.54) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL31495149 | 0.83 | MAPT (0.50) | L3MBTL1MAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL29463918 | 0.83 | MEN1 (0.56) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL19463676 | 0.83 | MEN1 (0.56) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL4947166 | 0.82 | KMT2A (0.61) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL30731266 | 0.81 | ALDH1A1 (0.54) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL21464058 | 0.81 | MAPT (0.47) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL30615393 | 0.81 | MAPT (0.47) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL397773 | 0.81 | MAPK1 (0.77) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 | |
| SCHEMBL19549667 | 0.81 | MAPK1 (0.50) | L3MBTL1MAPK1TDP1ALDH1A1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |