Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495051 | 0.84 | MAPT (0.49) | MAPTALDH1A1PKMPDE7AALPG | |
| SCHEMBL30615490 | 0.83 | L3MBTL1 (0.54) | MAPTALDH1A1PKMMAPK1SMN1; SMN2 | |
| SCHEMBL21467314 | 0.83 | L3MBTL1 (0.54) | MAPTALDH1A1PKMMAPK1SMN1; SMN2 | |
| SCHEMBL31495071 | 0.83 | MAPT (0.51) | MAPTALDH1A1PKMPDE7AMAPK1 | |
| SCHEMBL2329868 | 0.81 | L3MBTL1 (0.51) | MAPTALDH1A1PKMPDE7AMAPK1 | |
| SCHEMBL31495142 | 0.79 | TNF (0.41) | MAPTALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4929418 | 0.78 | MEN1 (0.61) | MAPTALDH1A1PKMPDE7AMAPK1 | |
| SCHEMBL8884629 | 0.77 | MAPK1 (0.56) | MAPTALDH1A1PKMPDE7AMAPK1 | |
| SCHEMBL31495025 | 0.77 | MEN1 (0.46) | MAPTPKMMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL31495028 | 0.76 | ALDH1A1 (0.41) | MAPTALDH1A1SMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |