Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17357067 | 0.97 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL19912624 | 0.97 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL13036887 | 0.97 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL10038490 | 0.97 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL19918239 | 0.89 | TSHR (0.37) | TSHR | |
| SCHEMBL17482142 | 0.87 | TSHR (0.36) | TSHR | |
| SCHEMBL10050936 | 0.87 | TSHR (0.36) | TSHR | |
| SCHEMBL820312 | 0.87 | TSHR (0.36) | TSHR | |
| SCHEMBL14586670 | 0.86 | TSHR (0.39) | TSHR | |
| SCHEMBL14365263 | 0.85 | TSHR (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794195-B1 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED ACRYLONITRILE-BASED POLYMERS, AND COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF | US GOVERNMENT (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8093343-B2 | Nitric oxide-releasing diazeniumdiolated compounds | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110282060-A1 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED COMPOUNDS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2011-11-17 | — | — | US | disclosed |
| US-7968664-B2 | Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070292471-A1 | Nitric Oxide-Releasing Diazeniumdiolated Acrylonitrile-Based Polymers, and Compositions, Medical Devices, and Uses Thereof | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALT (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070160521-A1 | Use of core/shell particles | MERCK PATENT GMBH (DE) | 2007-07-12 | — | — | US | disclosed |
| EP-1794195-A2 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED ACRYLONITRILE-BASED POLYMERS, AND COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF | The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037105-A2 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED ACRYLONITRILE-BASED POLYMERS, AND COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292471-A1 | Nitric Oxide-Releasing Diazeniumdiolated Acrylonitrile-Based Polymers, and Compositions, Medical Devices, and Uses Thereof | NOS2, NOS1, NOS3 | TSHR 3116/4885ALDH1A1 991/4885 |
| US-20110282060-A1 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED COMPOUNDS | NOS2, NOS1, NOS3 | TSHR 2358/4885ALDH1A1 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.