Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 9/20 | 0.83 |
| ▸ | DGKZ | Q13574 | 8/20 | 0.83 |
| ▸ | DGKI | O75912 | 3/20 | 0.83 |
| ▸ | DGKG | P49619 | 2/20 | 0.83 |
| ▸ | DGKB | Q9Y6T7 | 2/20 | 0.83 |
| ▸ | DGKK | Q5KSL6 | 1/20 | 0.83 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293196 | 1.00 | DGKA (0.83) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293351 | 0.95 | DGKA (0.79) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL30422106 | 0.95 | DGKA (0.79) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293353 | 0.95 | DGKA (0.79) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293267 | 0.93 | DGKA (0.72) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL21830991 | 0.91 | DGKA (1.00) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL29654799 | 0.91 | DGKA (1.00) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL30616441 | 0.90 | DGKZ (0.68) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293283 | 0.90 | DGKZ (0.68) | DGKADGKZDGKIDGKGDGKB | |
| SCHEMBL23293265 | 0.86 | DGKA (0.84) | DGKADGKZDGKIDGKGDGKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | claimed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |