Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587497 | 1.00 | NR4A2 (0.46) | NR4A2ACHEPARP1MAPTKDM5A | |
| SCHEMBL29706650 | 0.89 | KDM5A (0.48) | NR4A2PARP1KDM5AKDM5BCSNK2A1 | |
| SCHEMBL28739198 | 0.89 | KDM5A (0.48) | NR4A2PARP1KDM5AKDM5BCSNK2A1 | |
| SCHEMBL3236462 | 0.84 | ACHE (0.47) | NR4A2ACHEPARP1MAPTNPC1 | |
| SCHEMBL4561758 | 0.79 | NR4A2 (0.71) | NR4A2MAPTNPC1RAB9A | |
| SCHEMBL4140165 | 0.77 | PTGS1 (0.56) | ACHEMAPTRAB9AJAK2 | |
| SCHEMBL9959282 | 0.74 | ALDH1A1 (0.62) | MAPTNPC1RAB9A | |
| SCHEMBL14555878 | 0.74 | NR4A2 (0.46) | NR4A2PARP1MAPT | |
| SCHEMBL15173538 | 0.74 | NR4A2 (0.63) | NR4A2PARP1KDM5AKDM5BCSNK2A1 | |
| SCHEMBL4767790 | 0.73 | KLK6 (0.54) | ACHEPARP1MAPTCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114471412-B | Preparation method of substituted pyridopyrrole compound | 上海罕道医药科技有限公司 | 2023-09-26 | — | — | CN | disclosed |