SCHEMBL30620146

SCHEMBL30620146

CC(C(=O)O)c1cc2ccccc2[nH]1.O=C(O)CCc1cc2ccccc2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
PIN1 Q13526 1/20 0.48
ALOX5 P09917 1/20 0.46
ADAMTS4 O75173 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.41
CHRM1 P11229 1/20 0.41
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MAPT P10636 1/20 0.40
DAO P14920 1/20 0.40
HPGD P15428 1/20 0.40
SRD5A2 P31213 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875597 0.86 ALOX5 (0.57) ALOX5KDM4EHSD17B10MAPTDAO
SCHEMBL1767751 0.86 ALOX5 (0.57) ALOX5KDM4EHSD17B10MAPTDAO
SCHEMBL29417817 0.85 MTNR1A (0.60) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL606161 0.85 MTNR1A (0.60) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL29272703 0.83 MTNR1A (0.59) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL10759696 0.80 ALOX5 (0.51) MTNR1AMTNR1BALOX5KDM4EHSD17B10
SCHEMBL29353585 0.78 MTNR1A (0.56) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL143130 0.78 MTNR1A (0.56) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL28048759 0.78 MTNR1A (0.56) MTNR1AMTNR1BPIN1LOXL2CHRM1
SCHEMBL28610115 0.77 MTNR1A (0.47) MTNR1AMTNR1BPIN1ADAMTS4LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114569633-B Intestinal selective chelators for the treatment and prevention of autism and related disorders 轴向治疗公司 2023-11-17 CN disclosed