Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417817 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL29272703 | 0.98 | MTNR1A (0.59) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL29353585 | 0.92 | MTNR1A (0.56) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL28048759 | 0.92 | MTNR1A (0.56) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL143130 | 0.92 | MTNR1A (0.56) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28825523 | 0.90 | MTNR1A (0.55) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL6256471 | 0.90 | MTNR1A (0.55) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| SCHEMBL3887747 | 0.90 | MTNR1A (0.55) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| Naphthalene SCHEMBL28348414 | 0.90 | MTNR1A (0.55) | MTNR1AMTNR1BLOXL2PIN1KDM4E | |
| Potassium SCHEMBL3895695 | 0.90 | MTNR1A (0.55) | MTNR1AMTNR1BLOXL2PIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350456-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING INFLAMMATORY CONDITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-10-24 | — | — | US | claimed |
| US-11542540-B2 | Control nucleic acids, and compositions, kits, and uses thereof | Life Technologies Corporation (US) | 2023-01-03 | — | — | US | claimed |
| CN-115192716-A | Methods and systems for predicting, preventing or treating post-operative delirium | 中国人民解放军空军特色医学中心 | 2022-10-18 | — | — | CN | claimed |
| CN-114831984-A | Application of indolpropanoic acid in preparation of drug for preventing and/or treating nephritis | 滨州医学院 | 2022-08-02 | — | — | CN | claimed |
| CN-114438138-A | Metabolic composition prepared from clostridium sporogenes, and production method, detection method and application thereof | 重庆市畜牧科学院 | 2022-05-06 | — | — | CN | claimed |
| CN-113234009-B | Preparation method of nifedipine | 合肥立方制药股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| US-20220048979-A1 | TREATMENT OF STAPHYLOCOCCAL DISORDERS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS | 2022-02-17 | — | — | US | claimed |
| CN-113440522-A | Application of indolpropionic acid in preparation of drugs for treating autism | 中山大学附属第七医院(深圳) | 2021-09-28 | — | — | CN | claimed |
| CN-113234009-A | Preparation method of nifedipine | 合肥立方制药股份有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-112500392-A | C2-carbonyl ethyl indole derivative and preparation method and application thereof | 华南理工大学 | 2021-03-16 | — | — | CN | claimed |
| CN-111346081-A | New use of pharmaceutical composition comprising n-pentanoic acid, indolpropanic acid and sodium n-butyrate | 崔明 | 2020-06-30 | — | — | CN | claimed |
| CN-111253304-A | Preparation method of nifedipine | 合肥立方制药股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-111233672-A | Method for synthesizing nifedipine intermediate by using combined catalyst | 合肥立方制药股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| WO-2018071687-A1 | METHODS OF TREATING PRURITIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-19 | — | — | WO | claimed |
| EP-0715627-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | Pfizer Limited (GB) | 1996-06-12 | — | — | EP | claimed |
| EP-0609638-A1 | Water soluble polymeric systems of phytohormones with slow release: synthesis and application | Tsatsakis, Aristidis (GR) | 1994-08-10 | — | — | EP | claimed |
| EP-0251011-B1 | INDOLYL PROPIONIC ACIDS | BAYER AG (DE) | 1990-10-24 | — | — | EP | claimed |
| US-20250228870-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES FOR TREATING BRONCHIECTASIS | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | US | disclosed |
| US-4148796-A | γ-Piperidinobutyrophenones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-04-10 | — | — | US | disclosed |
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250228870-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES FOR TREATING BRONCHIECTASIS | DPEP1, TPP1, DPP9 | MTNR1A 1502/4885MTNR1B 1632/4885LOXL2 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.