SCHEMBL30620185

SCHEMBL30620185

C[Si](C)(C)C#Cc1ccc(C#C[Si](C)(C)C)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2C19 P33261 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
IMPDH2 P12268 1/20 0.35
IMPDH1 P20839 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20534467 1.00 CYP1A2 (0.41) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL12405322 0.86 KDM4E (0.39) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL5012545 0.83 GRM5 (0.49) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL18081447 0.83 ELANE (0.40) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL3839029 0.82 KDM4E (0.49) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL1470735 0.78 ALDH1A1 (0.35) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL29690232 0.78 ALDH1A1 (0.35) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL2055463 0.77 PLAU (0.39) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL10535351 0.76 TSHR (0.45) CYP1A2ALDH1A1CYP2C19KDM4EMEN1
SCHEMBL28468438 0.75 KDM4E (0.36) CYP1A2ALDH1A1CYP2C19KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003917-A Phenylene Polymer, method and use thereof 西蒙弗雷泽大学 2023-11-07 CN disclosed
CN-117003969-A Phenylene Polymer, method and use thereof 西蒙弗雷泽大学 2023-11-07 CN disclosed