Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623037 | 0.89 | NR1H2 (0.43) | GRM5NR1H2NR1H3MMP13 | |
| SCHEMBL30622819 | 0.88 | NR1H2 (0.37) | GRM5NR1H2NR1H3HTTKDM4E | |
| SCHEMBL24276770 | 0.86 | GRM5 (0.36) | GRM5NR1H2NR1H3ALDH1A1 | |
| SCHEMBL30622875 | 0.85 | GRM5 (0.50) | GRM5F2RL1HDAC2HDAC1TACR3 | |
| SCHEMBL26645190 | 0.85 | GRM5 (0.50) | GRM5F2RL1HDAC2HDAC1TACR3 | |
| SCHEMBL31692464 | 0.80 | LMNA (0.36) | GRM5NR1H2NR1H3KDM4EMEN1 | |
| SCHEMBL22279667 | 0.78 | MAP4K4 (0.39) | GRM5HDAC1NR1H2NR1H3MEN1 | |
| SCHEMBL26026951 | 0.78 | GRM5 (0.36) | GRM5NR1H2NR1H3KDM4EMEN1 | |
| SCHEMBL30622961 | 0.77 | GRM5 (0.46) | GRM5F2RL1HDAC2HDAC1HTT | |
| SCHEMBL30622799 | 0.77 | GRM5 (0.46) | GRM5F2RL1HDAC2HDAC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |