Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645190 | 1.00 | GRM5 (0.50) | GRM5TACR3ALDH1A1HPGDPRCP | |
| SCHEMBL26645434 | 0.86 | GRM5 (0.39) | GRM5TACR3MAPTNPC1RAB9A | |
| SCHEMBL26645493 | 0.85 | GRM5 (0.40) | GRM5TACR3LMNANPC1RAB9A | |
| SCHEMBL30622756 | 0.85 | GRM5 (0.45) | GRM5TACR3ALDH1A1HPGDKDM4E | |
| SCHEMBL26645151 | 0.75 | GRM5 (0.50) | GRM5TACR3MAPTF2RL1 | |
| SCHEMBL26645526 | 0.75 | GRM5 (0.50) | GRM5TACR3MAPTF2RL1 | |
| SCHEMBL30623037 | 0.74 | NR1H2 (0.43) | GRM5MAPTHDAC4HDAC6 | |
| SCHEMBL25433103 | 0.74 | GRM5 (0.41) | GRM5ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL26645168 | 0.74 | GRM5 (0.41) | GRM5ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL26645086 | 0.72 | CSNK1E (0.39) | GRM5TACR3ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |