Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622756 | 0.88 | GRM5 (0.45) | NR1H2NR1H3GRM5NTRK1KDM4E | |
| SCHEMBL26645493 | 0.86 | GRM5 (0.40) | GRM5 | |
| SCHEMBL30623037 | 0.84 | NR1H2 (0.43) | NR1H2NR1H3GRM5GPR119 | |
| SCHEMBL24276770 | 0.82 | GRM5 (0.36) | NR1H2NR1H3GRM5USP30UCHL1 | |
| SCHEMBL31692464 | 0.77 | LMNA (0.36) | NR1H2NR1H3GRM5USP30UCHL1 | |
| SCHEMBL22279667 | 0.75 | MAP4K4 (0.39) | NR1H2NR1H3GRM5UCHL1MEN1 | |
| SCHEMBL26026951 | 0.75 | GRM5 (0.36) | NR1H2NR1H3GRM5USP30UCHL1 | |
| SCHEMBL31362319 | 0.73 | GRM5 (0.35) | NR1H2NR1H3GRM5KDM4EMEN1 | |
| SCHEMBL30622875 | 0.72 | GRM5 (0.50) | GRM5CYP3A4KDM4EMEN1ALDH1A1 | |
| SCHEMBL26645190 | 0.72 | GRM5 (0.50) | GRM5CYP3A4KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |