Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622801 | 1.00 | NR1H2 (0.39) | NR1H2NR1H3SMOMAPTGPR119 | |
| SCHEMBL30622815 | 0.90 | CSNK1D (0.37) | SMOSETD7 | |
| SCHEMBL30622940 | 0.90 | CSNK1D (0.37) | SMOSETD7 | |
| SCHEMBL30622953 | 0.88 | KCNK3 (0.42) | SMOSETD7 | |
| SCHEMBL30622883 | 0.88 | KCNK3 (0.42) | SMOSETD7 | |
| SCHEMBL26645392 | 0.86 | SMO (0.43) | SMOTRPM2 | |
| SCHEMBL26645185 | 0.86 | SMO (0.43) | SMOTRPM2 | |
| SCHEMBL26645635 | 0.82 | MAPT (0.46) | MAPTGPR119CTSSENPP2 | |
| SCHEMBL30622921 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3SMOMAPTGPR119 | |
| SCHEMBL26645124 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3SMOMAPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |