Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | TACR3 | P29371 | 4/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CPS1 | P31327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622819 | 0.86 | NR1H2 (0.37) | GRM5 | |
| SCHEMBL30622875 | 0.85 | GRM5 (0.50) | GRM5TACR3NPC1LMNARAB9A | |
| SCHEMBL26645190 | 0.85 | GRM5 (0.50) | GRM5TACR3NPC1LMNARAB9A | |
| SCHEMBL26645434 | 0.80 | GRM5 (0.39) | GRM5TACR3TACR2TACR1NPC1 | |
| SCHEMBL30622756 | 0.72 | GRM5 (0.45) | GRM5TACR3 | |
| SCHEMBL25433103 | 0.70 | GRM5 (0.41) | GRM5SMN1; SMN2 | |
| SCHEMBL26645168 | 0.70 | GRM5 (0.41) | GRM5SMN1; SMN2 | |
| SCHEMBL30623037 | 0.68 | NR1H2 (0.43) | GRM5 | |
| SCHEMBL25431709 | 0.67 | GRM5 (0.39) | GRM5 | |
| SCHEMBL25434081 | 0.67 | GRM5 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |