Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 12/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.61 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.61 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625242 | 0.92 | GRIN2B (0.60) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL10153811 | 0.87 | GRIN2B (0.69) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL4286977 | 0.87 | GRIN2B (0.69) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL29532829 | 0.86 | GRIN2B (0.67) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL1495904 | 0.86 | GRIN2B (0.67) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL618588 | 0.85 | SMN1; SMN2 (0.71) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL34466702 | 0.84 | GRIN2B (0.62) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL23301123 | 0.84 | SMN1; SMN2 (0.69) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL696467 | 0.84 | SMN1; SMN2 (0.69) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL5366902 | 0.84 | TPSAB1 (0.72) | GRIN2BCYP2D6CYP2C9SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270213-A1 | PI3Ka INHIBITORS | PIKAVATION THERAPEUTICS, INC. | 2025-08-28 | — | — | US | disclosed |
| CN-119654321-A | PI3K alpha inhibitors | 突触活化疗法股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-4511373-A1 | PI3K? INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270213-A1 | PI3Ka INHIBITORS | PIK3CA, PIK3C2A, PIK3R5 | GRIN2B 2502/4885CYP2D6 4741/4885CYP2C9 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.