SCHEMBL618588

SCHEMBL618588

NCC1CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.71
CYP2C19 P33261 1/20 0.71
NPC1 O15118 2/20 0.70
RAB9A P51151 2/20 0.70
TPSAB1 Q15661 2/20 0.69
TPSD1 Q9BZJ3 2/20 0.69
TPSG1 Q9NRR2 2/20 0.69
GRIN2B Q13224 10/20 0.62
CYP2D6 P10635 4/20 0.61
CYP2C9 P11712 4/20 0.61
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
CYP3A4 P08684 3/20 0.58
HTT P42858 1/20 0.56
FAAH O00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23301123 0.99 SMN1; SMN2 (0.69) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL17453711 0.95 SMN1; SMN2 (0.64) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL5351012 0.92 SMN1; SMN2 (0.64) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL4364637 0.89 SMN1; SMN2 (0.67) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
Hydrochloric Acid SCHEMBL14157232 0.88 SMN1; SMN2 (0.66) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL458805 0.87 SMN1; SMN2 (0.72) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL15140566 0.87 SMN1; SMN2 (0.72) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL21681858 0.87 SMN1; SMN2 (0.59) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL5348136 0.86 TPSAB1 (0.70) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1
SCHEMBL5346990 0.86 TPSAB1 (0.70) SMN1; SMN2CYP2C19NPC1RAB9ATPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-06-19 US disclosed
EP-4516321-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-03-05 EP disclosed
US-11858941-B2 Heterocyclic and heteroaryl compounds for treating Huntington's disease PTC THERAPEUTICS, INC. (US) 2024-01-02 US disclosed
WO-2023207710-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2023-11-02 WO disclosed
US-20230024096-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER C4 THERAPEUTICS, INC. 2023-01-26 US disclosed
EP-4051674-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2022-09-07 EP disclosed
WO-2021083949-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2021-05-06 WO disclosed
EP-3666758-A1 PROCESS FOR THE PREPARATION OF A SULFONAMIDE DERIVATIVE AbbVie Inc. (US) 2020-06-17 EP disclosed
EP-3008045-B1 ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS ANTABIO SAS (FR) 2018-05-09 EP disclosed
US-9771374-B2 Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof INNOV17 LLC (US) 2017-09-26 US disclosed
EP-1058683-A1 FARNESYL TRANSFERASE INHIBITORS HAVING A PIPERIDINE STRUCTURE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LIMITED (KR) 2000-12-13 EP disclosed
EP-1045846-A1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LIMITED (KR) 2000-10-25 EP disclosed
EP-1000036-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LIMITED (KR) 2000-05-17 EP disclosed
WO-1999038862-A1 FARNESYL TRANSFERASE INHIBITORS HAVING A PIPERIDINE STRUCTURE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD. (KR) 1999-08-05 WO disclosed
WO-1999028315-A1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD. (KR) 1999-06-10 WO disclosed
WO-1999005117-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LTD. (KR) 1999-02-04 WO disclosed
US-5648368-A ANTICOAGULANTS MERCK & CO., INC. (US) 1997-07-15 US disclosed
EP-0673247-A4 FIBRINOGEN RECEPTOR ANTAGONISTS. MERCK & CO INC (US) 1996-05-01 EP disclosed
EP-0673247-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1995-09-27 EP disclosed
WO-1994012181-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195683-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEROF CD47, ABCB1, EGFR SMN1; SMN2 2540/4885CYP2C19 131/4885NPC1 2026/4885
US-11858941-B2 Heterocyclic and heteroaryl compounds for treating Huntington's disease HTT, HYPK, FH SMN1; SMN2 186/4885CYP2C19 801/4885NPC1 138/4885
US-20230024096-A1 BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER SMARCC1, SMARCC2, SMARCA2 SMN1; SMN2 336/4885CYP2C19 4593/4885NPC1 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.