Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087477 | 1.00 | NAMPT (0.42) | NAMPTL3MBTL1DYRK1AKLKB1GRM2 | |
| SCHEMBL30625715 | 0.89 | CHRM4 (0.48) | NAMPTL3MBTL1DYRK1AGRM2CYP3A4 | |
| SCHEMBL10264167 | 0.89 | CHRM4 (0.48) | NAMPTL3MBTL1DYRK1AGRM2CYP3A4 | |
| SCHEMBL30625719 | 0.86 | ACACB (0.43) | NAMPTL3MBTL1DYRK1A | |
| SCHEMBL30625718 | 0.85 | NAMPT (0.43) | NAMPTL3MBTL1DYRK1AGRM2CYP3A4 | |
| SCHEMBL26602958 | 0.83 | CHRM4 (0.43) | NAMPTKLKB1CHRM4MAPK1 | |
| SCHEMBL5018970 | 0.82 | L3MBTL1 (0.43) | NAMPTL3MBTL1GRM2CYP3A4KDM4A | |
| SCHEMBL14923665 | 0.80 | SYK (0.47) | NAMPTSYK | |
| SCHEMBL18854481 | 0.77 | EPAS1 (0.43) | NAMPTL3MBTL1DYRK1AGRM2KDM4A | |
| SCHEMBL28394419 | 0.76 | AAK1 (0.47) | NAMPTL3MBTL1DYRK1AGRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084036-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND THERAPEUTIC AND/OR PROPHYLACTIC DRUG | ALCHEMEDICINE, INC. (JP) | 2025-03-13 | — | — | US | disclosed |
| EP-4512468-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | Alchemedicine, Inc. (JP) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023204292-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND TREATMENT AND/OR PREVENTATIVE DRUG | 株式会社アークメディスン | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084036-A1 | COMPOUND, ALDEHYDE DEHYDROGENASE 2 ACTIVATOR, PHARMACEUTICAL COMPOSITION, AND THERAPEUTIC AND/OR PROPHYLACTIC DRUG | ALDH3A1, ALDH2, ALDH1A1 | NAMPT 984/4885L3MBTL1 1609/4885DYRK1A 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.