Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375315 | 1.00 | METAP2 (0.50) | METAP2KMT2AOPRK1RAB9ACCR1 | |
| SCHEMBL7519332 | 0.79 | CCR1 (0.46) | METAP2KMT2AOPRK1RAB9ACCR1 | |
| SCHEMBL5264584 | 0.76 | TGFBR1 (0.45) | METAP2KMT2ARAB9ACCR1CCR5 | |
| SCHEMBL3372322 | 0.76 | CCR1 (0.43) | METAP2KMT2ARAB9ACCR1CCR5 | |
| SCHEMBL30509534 | 0.76 | CCR1 (0.43) | METAP2KMT2ARAB9ACCR1CCR5 | |
| SCHEMBL24422536 | 0.76 | ACHE (0.39) | METAP2KMT2ARAB9AACHEKDM4E | |
| SCHEMBL29472071 | 0.76 | ACHE (0.39) | METAP2KMT2AOPRK1RAB9AACHE | |
| SCHEMBL29582518 | 0.76 | ACHE (0.39) | METAP2KMT2ARAB9AACHEKDM4E | |
| SCHEMBL21199865 | 0.76 | ACHE (0.39) | METAP2KMT2ARAB9AACHEKDM4E | |
| SCHEMBL796213 | 0.76 | ACHE (0.39) | METAP2KMT2AOPRK1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981667-A | Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment | 蝎子疗法股份有限公司 | 2023-10-31 | — | — | CN | disclosed |