Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625922 | 0.82 | HDAC3 (0.48) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL20764432 | 0.79 | ALDH1A1 (0.43) | LMNAALDH1A1TP53MAPK1ROCK2 | |
| SCHEMBL20764430 | 0.79 | ALDH1A1 (0.43) | LMNAALDH1A1TP53MAPK1ROCK2 | |
| SCHEMBL22076738 | 0.78 | NAMPT (0.41) | LMNAALDH1A1TP53MAPK1ROCK2 | |
| SCHEMBL22076737 | 0.78 | NAMPT (0.41) | LMNAALDH1A1TP53MAPK1ROCK2 | |
| SCHEMBL21138155 | 0.78 | EP300 (0.48) | LMNAALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL26543681 | 0.77 | PLG (0.38) | LMNAALDH1A1TP53MAPK1POLB | |
| SCHEMBL21137817 | 0.76 | GAA (0.42) | LMNAALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL22099920 | 0.76 | POLB (0.40) | LMNAALDH1A1TP53MAPK1POLB | |
| SCHEMBL26544999 | 0.76 | PLG (0.37) | LMNAALDH1A1TP53MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997627-B | Cyst amide derivatives | 亥姆霍兹感染研究中心有限公司 | 2023-10-10 | — | — | CN | disclosed |