Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21137817 | 0.86 | GAA (0.42) | EP300SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL24379797 | 0.86 | EP300 (0.53) | EP300SMN1; SMN2LMNAHIF1ABCL2 | |
| SCHEMBL16392463 | 0.85 | EP300 (0.57) | EP300LMNAHIF1ABCL2BCL2L1 | |
| SCHEMBL22571840 | 0.81 | EP300 (0.47) | EP300SMN1; SMN2HIF1ABCL2BCL2L1 | |
| SCHEMBL20786981 | 0.80 | MITF (0.42) | EP300SMN1; SMN2LMNAPOLBMCL1 | |
| SCHEMBL16369610 | 0.80 | EP300 (0.63) | EP300LMNAHIF1ABCL2BCL2L1 | |
| SCHEMBL17784953 | 0.79 | EP300 (0.56) | EP300LMNAHIF1ABCL2BCL2L1 | |
| SCHEMBL30625925 | 0.78 | LMNA (0.47) | SMN1; SMN2LMNAPOLBMAPTHTT | |
| SCHEMBL17784957 | 0.78 | EP300 (0.58) | EP300LMNAHIF1ABCL2BCL2L1 | |
| SCHEMBL17775416 | 0.77 | EP300 (0.48) | EP300LMNAHIF1ABCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793600-B2 | Cystobactamides | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-10-06 | — | — | US | disclosed |
| US-20190185514-A1 | CYSTOBACTAMIDES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185514-A1 | CYSTOBACTAMIDES | CTH, SLC7A11, SULT2A1 | EP300 3359/4885SMN1; SMN2 4462/4885LMNA 4548/4885 |
| US-10793600-B2 | Cystobactamides | CTH, SLC7A11, SULT2A1 | EP300 3514/4885SMN1; SMN2 4430/4885LMNA 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.