Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | CPS1 | P31327 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420711 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2APARP10KAT6APDK2 | |
| SCHEMBL30087619 | 0.86 | PARP10 (0.46) | ALDH1A1KMT2APARP10KAT6APDK2 | |
| SCHEMBL17420410 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2APARP10KAT6APDK2 | |
| SCHEMBL30628317 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2APARP10KAT6APDK2 | |
| SCHEMBL17420600 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2APARP10PDK2PTPN5 | |
| SCHEMBL30628301 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2APARP10PDK2PTPN5 | |
| SCHEMBL17420677 | 0.81 | NPSR1 (0.39) | ALDH1A1KMT2APARP10PDK2FFAR4 | |
| SCHEMBL30628215 | 0.81 | PDE2A (0.44) | ALDH1A1FFAR4POLB | |
| SCHEMBL17420715 | 0.81 | PDE2A (0.44) | ALDH1A1FFAR4POLB | |
| SCHEMBL7815438 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2APARP10KAT6APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |