Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420715 | 1.00 | PDE2A (0.44) | PDE2APIM1FFAR4FFAR1PTGS1 | |
| SCHEMBL30087609 | 0.85 | PDE2A (0.43) | PDE2APIM1FFAR4FFAR1PTGS1 | |
| SCHEMBL17420477 | 0.82 | FFAR4 (0.43) | PIM1FFAR4FFAR1PTGS1PTGS2 | |
| SCHEMBL30628322 | 0.82 | FFAR4 (0.43) | PIM1FFAR4FFAR1PTGS1PTGS2 | |
| SCHEMBL27176579 | 0.82 | AKR1C2 (0.46) | PIM1FFAR4FFAR1EPHX2AURKA | |
| SCHEMBL30628206 | 0.81 | ALDH1A1 (0.46) | FFAR4ALDH1A1POLB | |
| SCHEMBL17420711 | 0.81 | ALDH1A1 (0.46) | FFAR4ALDH1A1POLB | |
| SCHEMBL17420469 | 0.79 | POLB (0.46) | PDE2AFFAR4FFAR1ALDH1A1POLB | |
| SCHEMBL30628289 | 0.77 | KCNN4 (0.51) | ALDH1A1 | |
| SCHEMBL17420624 | 0.77 | KCNN4 (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |