SCHEMBL30087619

SCHEMBL30087619

CC(C)Oc1ccc(C(F)(F)C(N)=O)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 1/20 0.46
▸ GLA P06280 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.41
▸ IRAK4 Q9NWZ3 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ PDK2 Q15119 1/20 0.39
▸ BRD4 O60885 1/20 0.39
▸ BRPF1 P55201 1/20 0.39
▸ PTPN5 P54829 2/20 0.38
▸ PRSS1 P07477 2/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP3A5 P20815 1/20 0.38
▸ TMPRSS15 P98073 1/20 0.38
▸ SLC7A5 Q01650 2/20 0.38
▸ CPS1 P31327 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17420711 0.86 ALDH1A1 (0.46) PARP10ALDH1A1KMT2APDK2PTPN5
SCHEMBL30628206 0.86 ALDH1A1 (0.46) PARP10ALDH1A1KMT2APDK2PTPN5
SCHEMBL30087654 0.85 PARP10 (0.46) PARP10GLAALDH1A1IRAK4KMT2A
SCHEMBL30087600 0.85 PARP10 (0.46) PARP10GLAALDH1A1IRAK4KMT2A
SCHEMBL30087609 0.81 PDE2A (0.43) KMT2AGAA
SCHEMBL7815438 0.80 ALDH1A1 (0.41) PARP10GLAALDH1A1KMT2APDK2
SCHEMBL17420677 0.80 NPSR1 (0.39) PARP10ALDH1A1KMT2APDK2CYP3A4
SCHEMBL30087653 0.78 IRAK4 (0.43) PARP10ALDH1A1IRAK4PRSS1POLB
SCHEMBL30087591 0.78 PARP10 (0.56) PARP10GLAALDH1A1IRAK4KMT2A
SCHEMBL3710890 0.74 KIF11 (0.51) KMT2ASLC7A5KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2025-10-16 — — US disclosed
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2023-08-03 — — US disclosed
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same DEUTERX, LLC (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 PARP10 1604/4885GLA 3201/4885ALDH1A1 2487/4885
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 PARP10 1604/4885GLA 3201/4885ALDH1A1 2487/4885
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same EGLN3, HPGDS, EGLN2 PARP10 1604/4885GLA 3201/4885ALDH1A1 2487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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