SCHEMBL30087609

SCHEMBL30087609

NC(=O)C(F)(F)c1ccc(OC(F)(F)F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PDE2A O00408 4/20 0.43
▸ PIM1 P11309 1/20 0.42
▸ EPHX2 P34913 2/20 0.40
▸ FFAR4 Q5NUL3 3/20 0.39
▸ FFAR1 O14842 2/20 0.39
▸ EPHX1 P07099 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ GPR3 P46089 2/20 0.39
▸ PTGS1 P23219 1/20 0.38
▸ PTGS2 P35354 1/20 0.38
▸ KCNN4 O15554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17420715 0.85 PDE2A (0.44) PDE2APIM1EPHX2FFAR4FFAR1
SCHEMBL30628215 0.85 PDE2A (0.44) PDE2APIM1EPHX2FFAR4FFAR1
SCHEMBL30087715 0.83 PIM1 (0.41) PDE2APIM1EPHX2FFAR4EPHX1
SCHEMBL30087619 0.81 PARP10 (0.46) GAAKMT2A
SCHEMBL17420469 0.78 POLB (0.46) PDE2AFFAR4FFAR1
SCHEMBL14155817 0.78 PDE2A (0.45) PDE2AKDM4EGAAGPR3
SCHEMBL29177399 0.77 EPHX2 (0.45) PDE2APIM1EPHX2FFAR4FFAR1
SCHEMBL22092981 0.77 DGAT1 (0.51) PIM1EPHX2FFAR4FFAR1KDM4E
SCHEMBL30087624 0.75 EPHX2 (0.43) PDE2AEPHX2FFAR4GPR3KCNN4
SCHEMBL28958691 0.74 EPHX2 (0.53) PDE2APIM1EPHX2KMT2AKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2025-10-16 — — US disclosed
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2023-08-03 — — US disclosed
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same DEUTERX, LLC (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 PDE2A 630/4885PIM1 2626/4885EPHX2 1251/4885
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME EGLN3, HPGDS, EGLN2 PDE2A 630/4885PIM1 2626/4885EPHX2 1251/4885
US-11535603-B1 Deuterium-enriched piperidinonyl-oxoisoindolinyl acetamides and methods of treating medical disorders using same EGLN3, HPGDS, EGLN2 PDE2A 630/4885PIM1 2626/4885EPHX2 1251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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