Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21427196 | 1.00 | TACR2 (0.53) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30880067 | 0.96 | TACR2 (0.52) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21427052 | 0.96 | TACR2 (0.52) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30467215 | 0.94 | FDPS (0.55) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7141110 | 0.94 | FDPS (0.55) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5213944 | 0.93 | TACR2 (0.54) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9077155 | 0.93 | TACR2 (0.54) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL29721221 | 0.93 | TACR2 (0.54) | TACR2MAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21427194 | 0.90 | FDPS (0.54) | MAOAMAOBSMN1; SMN2ALDH1A1C5AR1 | |
| SCHEMBL30467197 | 0.90 | FDPS (0.54) | MAOAMAOBSMN1; SMN2ALDH1A1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | AUTOTAC INC. (KR) | 2025-09-30 | — | — | US | disclosed |
| US-11981618-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | AUTOTAC INC. (KR) | 2024-05-14 | — | — | US | disclosed |
| CN-112672993-B | Novel AUTOTAC chimeric compounds and compositions comprising same for preventing, ameliorating or treating diseases by targeted protein degradation | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-112424159-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 普罗泰克株式会社 | 2023-10-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | SQSTM1, ATG7, BECN1 | TACR2 4471/4885MAOA 4624/4885MAOB 4703/4885 |
| US-11981618-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | SQSTM1, ATG7, BECN1 | TACR2 4532/4885MAOA 4814/4885MAOB 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.