SCHEMBL30628992

SCHEMBL30628992

C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 3/20 0.61
OPRM1 P35372 2/20 0.59
OPRD1 P41143 2/20 0.59
MAGI3 Q5TCQ9 1/20 0.55
KISS1R Q969F8 2/20 0.53
ACE P12821 1/20 0.53
ERAP2 Q6P179 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29507360 0.93 OPRM1 (0.67) GHSROPRM1OPRD1ACE
SCHEMBL30799518 0.90 GHSR (0.63) GHSR
SCHEMBL31575718 0.89 OPRM1 (0.58) GHSROPRM1OPRD1KISS1RERAP2
SCHEMBL29351069 0.89 OPRM1 (0.66) GHSROPRM1OPRD1ACE
SCHEMBL30506399 0.88 LTA4H (0.56) GHSROPRM1OPRD1ACEERAP2
SCHEMBL22366987 0.88 GHSR (0.57) GHSROPRM1OPRD1ACE
SCHEMBL22366988 0.88 GHSR (0.57) GHSROPRM1OPRD1ACE
SCHEMBL30799531 0.88 GHSR (0.72) GHSROPRM1OPRD1
SCHEMBL30051359 0.88 ACE (0.64) GHSROPRM1OPRD1ACEERAP2
SCHEMBL31146519 0.88 GHSR (0.61) GHSRKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 US disclosed
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-11 US disclosed
EP-4499663-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS Provincial Health Services Authority (CA) 2025-02-05 EP disclosed
CN-119213011-A Radiolabeled compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2024-12-27 CN disclosed
US-20240123099-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-04-18 US disclosed
WO-2023178449-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders GRPR, NPY5R, NPY2R GHSR 116/4885OPRM1 179/4885OPRD1 252/4885
US-20240123099-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R GHSR 116/4885OPRM1 179/4885OPRD1 252/4885
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R GHSR 135/4885OPRM1 166/4885OPRD1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.