Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424124 | 1.00 | EPHX2 (0.39) | EPHX2MEN1KMT2AKDM5ASMO | |
| SCHEMBL29243829 | 0.92 | MEN1 (0.41) | EPHX2MEN1KMT2ASMOACHE | |
| SCHEMBL29585836 | 0.92 | MEN1 (0.41) | EPHX2MEN1KMT2ASMOACHE | |
| SCHEMBL24424319 | 0.89 | CDK9 (0.39) | EPHX2MEN1KMT2ASMOGAA | |
| SCHEMBL24424139 | 0.89 | KDM5A (0.37) | EPHX2MEN1KMT2AKDM5ASMO | |
| SCHEMBL24423608 | 0.89 | KDM5A (0.39) | EPHX2MEN1KMT2AKDM5ASMO | |
| SCHEMBL29585485 | 0.87 | SMO (0.41) | EPHX2MEN1KMT2AKDM5ASMO | |
| SCHEMBL24423840 | 0.86 | SMO (0.43) | EPHX2MEN1KMT2ASMOACHE | |
| SCHEMBL24424028 | 0.86 | ALDH1A1 (0.38) | EPHX2MEN1KMT2AKDM5ASMO | |
| SCHEMBL29584832 | 0.86 | SMO (0.38) | EPHX2MEN1KMT2AKDM5ASMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |