Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089250 | 0.91 | CHRNB2 (0.44) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL31330395 | 0.91 | CHRNB2 (0.44) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL27676284 | 0.83 | TRPC6 (0.43) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL25191769 | 0.83 | TRPC6 (0.43) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL24746050 | 0.81 | HDAC1 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL29891180 | 0.81 | HDAC1 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL29644776 | 0.79 | NOTUM (0.45) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL29813774 | 0.79 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3MAPT | |
| SCHEMBL1394162 | 0.78 | CHRNB2 (0.42) | CHRNB2CHRNA4GABRPGABRDGABRA1 | |
| SCHEMBL16872560 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |