Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423705 | 1.00 | HCAR2 (0.42) | HCAR2DAOMEN1KMT2APOLB | |
| SCHEMBL24423696 | 0.88 | MAPK1 (0.46) | MEN1KMT2APOLBKDM4ENNMT | |
| SCHEMBL29584762 | 0.88 | MAPK1 (0.46) | MEN1KMT2APOLBKDM4ENNMT | |
| SCHEMBL24424513 | 0.84 | HCAR2 (0.41) | HCAR2DAOMEN1KMT2APOLB | |
| SCHEMBL29586549 | 0.84 | HCAR2 (0.41) | HCAR2DAOMEN1KMT2APOLB | |
| SCHEMBL24424531 | 0.82 | HCAR2 (0.46) | HCAR2DAOMEN1KMT2APOLB | |
| SCHEMBL29585218 | 0.81 | NPC1 (0.40) | MEN1KMT2APOLB | |
| SCHEMBL29584681 | 0.80 | GAA (0.40) | KMT2A | |
| SCHEMBL24423445 | 0.80 | GAA (0.40) | KMT2A | |
| SCHEMBL24423338 | 0.79 | MGLL (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156380-A | Solid crystalline forms of PPAR-gamma modulators and methods of use thereof | 卫材R&D管理有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |