Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423696 | 1.00 | MAPK1 (0.46) | MAPK1MEN1KMT2AL3MBTL1ALPL | |
| SCHEMBL30630483 | 0.88 | HCAR2 (0.42) | MEN1KMT2APOLBNNMTKDM4E | |
| SCHEMBL24423705 | 0.88 | HCAR2 (0.42) | MEN1KMT2APOLBNNMTKDM4E | |
| SCHEMBL24423852 | 0.86 | MAPK1 (0.47) | MAPK1MEN1KMT2AL3MBTL1ALPL | |
| SCHEMBL29585218 | 0.80 | NPC1 (0.40) | MEN1KMT2AALPLNPC1POLB | |
| SCHEMBL24423965 | 0.78 | MGLL (0.39) | CRBNEGLN1 | |
| SCHEMBL24423338 | 0.78 | MGLL (0.39) | CRBNEGLN1 | |
| SCHEMBL24423091 | 0.78 | MGLL (0.39) | CRBNEGLN1 | |
| SCHEMBL24423068 | 0.78 | MGLL (0.39) | CRBNEGLN1 | |
| SCHEMBL24423081 | 0.78 | MGLL (0.39) | CRBNEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522605-A1 | SOLID FORM OF PPAR-GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2025-03-19 | — | — | EP | disclosed |
| CN-119156380-A | Solid crystalline forms of PPAR-gamma modulators and methods of use thereof | 卫材R&D管理有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023219879-A1 | SOLID FORM OF PPAR-gamma MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-11-16 | — | — | WO | disclosed |
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |