Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM5A | P29375 | 9/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24422914 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM5ARAB9AKDM5BMEN1 | |
| SCHEMBL29585699 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KDM5APARP1RAB9ANPC1 | |
| SCHEMBL29585365 | 0.85 | RAB9A (0.40) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL29584646 | 0.84 | TLR8 (0.36) | ALDH1A1KDM5APARP1 | |
| SCHEMBL25090954 | 0.84 | TLR8 (0.36) | ALDH1A1KDM5APARP1 | |
| SCHEMBL24423639 | 0.82 | MEN1 (0.46) | ALDH1A1KDM5AKDM5BMEN1KMT2A | |
| SCHEMBL24423643 | 0.80 | PTGES (0.45) | ALDH1A1KDM5AKDM5BMEN1KMT2A | |
| SCHEMBL29584591 | 0.80 | PTGES (0.45) | ALDH1A1KDM5AKDM5BMEN1KMT2A | |
| SCHEMBL24423862 | 0.78 | RAB9A (0.41) | ALDH1A1KDM5ARAB9AKDM5BMEN1 | |
| SCHEMBL24423445 | 0.78 | GAA (0.40) | KDM5ARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |