Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816862 | 1.00 | CXCL8 (0.43) | CXCL8CYP2C9C1RHDAC3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL29514703 | 0.93 | ALDH1A1 (0.40) | CXCL8CYP2C9C1RHDAC3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL22608513 | 0.93 | ALDH1A1 (0.40) | CXCL8CYP2C9C1RHDAC3HDAC1 | |
| SCHEMBL11334107 | 0.80 | MEN1 (0.49) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL22608515 | 0.80 | MAPT (0.38) | CXCL8CYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL22608548 | 0.79 | KMO (0.47) | HDAC3HDAC1HDAC2HDAC6MEN1 | |
| SCHEMBL30631902 | 0.78 | HAO1 (0.41) | MEN1KMT2APOLBHAO1ALPL | |
| SCHEMBL22816548 | 0.78 | HAO1 (0.41) | MEN1KMT2APOLBHAO1ALPL | |
| SCHEMBL22608748 | 0.78 | HAO1 (0.38) | C1RMEN1KMT2AHAO1ALDH1A1 | |
| SCHEMBL29490663 | 0.78 | HAO1 (0.38) | C1RMEN1KMT2AHAO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |