SCHEMBL30632548

SCHEMBL30632548

CC(=O)N1CC2(CC(c3ccc4cc(O)nnc4c3)C2)C1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ QDPR P09417 2/20 0.38
▸ MGLL Q99685 8/20 0.36
▸ SCD5 Q86SK9 1/20 0.35
▸ CHRM4 P08173 1/20 0.32
▸ CHRM1 P11229 1/20 0.32
▸ AVPR1A P37288 3/20 0.32
▸ PDE10A Q9Y233 1/20 0.32
▸ AVPR2 P30518 1/20 0.31
▸ KRAS P01116 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ PDCD1LG2 Q9BQ51 1/20 0.31
▸ CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30632561 0.84 SMARCA2 (0.41) QDPRMGLLSCD5PDE10APDCD1LG2
SCHEMBL26685131 0.84 QDPR (0.42) QDPRSCD5PDE10A
SCHEMBL31570183 0.84 QDPR (0.42) QDPRSCD5PDE10A
SCHEMBL26888672 0.81 QDPR (0.59) QDPRPDE10A
SCHEMBL31570146 0.74 QDPR (0.42) QDPR
SCHEMBL26685025 0.74 QDPR (0.42) QDPR
SCHEMBL31570168 0.68 SMARCA2 (0.47) QDPR
SCHEMBL26685057 0.68 SMARCA2 (0.47) QDPR
SCHEMBL30632506 0.66 MGLL (0.38) QDPRMGLLSCD5AVPR1AAVPR2
SCHEMBL26685079 0.64 DPP4 (0.39) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998278-A Compounds and uses thereof 福宏治疗公司 2025-05-13 — — CN disclosed
EP-4522278-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES Foghorn Therapeutics Inc. (US) 2025-03-19 — — EP disclosed
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 — — WO disclosed
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