Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 6/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686416 | 1.00 | NUDT1 (0.38) | NUDT1TBK1CHUKINSRMAPK8 | |
| SCHEMBL30633151 | 0.83 | CHUK (0.37) | NUDT1TBK1CHUKINSRMAPK8 | |
| SCHEMBL26685805 | 0.83 | CHUK (0.37) | NUDT1TBK1CHUKINSRMAPK8 | |
| SCHEMBL26686177 | 0.83 | IKBKB (0.42) | TBK1CHUKCLK2CLK3DYRK1A | |
| SCHEMBL30633136 | 0.83 | NUDT1 (0.44) | NUDT1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL26685815 | 0.83 | NUDT1 (0.44) | NUDT1CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL26686016 | 0.80 | IKBKB (0.44) | TBK1CHUK | |
| SCHEMBL26686186 | 0.79 | BRD4 (0.43) | NUDT1CHUKMAPK8CLK2DYRK1A | |
| SCHEMBL31420163 | 0.79 | BRD4 (0.43) | NUDT1CHUKMAPK8CLK2DYRK1A | |
| SCHEMBL26686245 | 0.79 | CDK9 (0.42) | TBK1CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | claimed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | claimed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |