Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113495 | 0.82 | DGAT1 (0.39) | TYK2HCRTR1HCRTR2JAK1KCNH2 | |
| SCHEMBL23761304 | 0.80 | MAPK14 (0.40) | TYK2HCAR1MAPK14JAK1KCNH2 | |
| SCHEMBL2276295 | 0.73 | AOC3 (0.48) | MEN1KMT2APPARALMNA | |
| SCHEMBL2659856 | 0.71 | AHR (0.45) | KDM4EHPGDTSHRHCRTR1MEN1 | |
| SCHEMBL2945910 | 0.71 | S100A4 (0.46) | LMNA | |
| SCHEMBL1441262 | 0.70 | DGAT1 (0.45) | KDM4EPKM | |
| SCHEMBL15868146 | 0.70 | AOC3 (0.37) | HPGDTSHRPPARA | |
| SCHEMBL31415394 | 0.70 | PLA2G7 (0.40) | TYK2KDM4EHPGDTSHRHCRTR1 | |
| SCHEMBL23837827 | 0.70 | IDO1 (0.41) | TYK2KDM4EHCAR1HCRTR1HCRTR2 | |
| SCHEMBL481810 | 0.70 | CYP4F2 (0.36) | CRHR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043162-A | TYK2 selective inhibitors and uses thereof | 迈巴制药(南京)有限公司 | 2023-11-10 | — | — | CN | disclosed |