SCHEMBL30633641

SCHEMBL30633641

C#Cc1ccc2c(c1)c(-c1cccc(S(=O)(=O)N(C)C)c1)c(C)n2C/C(F)=C/CNC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 20/20 0.56
DAO P14920 2/20 0.56
AOC3 Q16853 2/20 0.56
LOX P28300 2/20 0.56
LOXL3 P58215 2/20 0.56
LOXL1 Q08397 2/20 0.56
LOXL4 Q96JB6 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23745927 1.00 LOXL2 (0.56) LOXL2DAOAOC3LOXLOXL3
SCHEMBL19255070 0.93 LOXL2 (0.56) LOXL2DAOAOC3LOXLOXL3
SCHEMBL20713693 0.90 LOXL2 (0.60) LOXL2DAOAOC3LOXLOXL3
SCHEMBL23723369 0.90 LOXL2 (0.63) LOXL2DAOAOC3LOXLOXL3
SCHEMBL23723365 0.90 LOXL2 (0.63) LOXL2DAOAOC3LOXLOXL3
SCHEMBL19255222 0.90 LOXL2 (0.61) LOXL2DAOAOC3LOXLOXL3
SCHEMBL20699710 0.88 LOXL2 (0.72) LOXL2DAOAOC3LOXLOXL3
SCHEMBL19255696 0.88 LOXL2 (0.72) LOXL2DAOAOC3LOXLOXL3
SCHEMBL19255414 0.88 LOXL2 (0.57) LOXL2DAOAOC3LOXLOXL3
SCHEMBL19255099 0.88 LOXL2 (0.57) LOXL2DAOAOC3LOXLOXL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO LOXL2 25/4885DAO 6/4885AOC3 7/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 LOXL2 3/4885DAO 10/4885AOC3 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.