Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 2/20 | 0.44 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635494 | 0.84 | CACNA1B (0.50) | MAPTBACE1MEN1KMT2AKDM4E | |
| SCHEMBL3053519 | 0.82 | CACNA1B (0.47) | MAPTMEN1KMT2AKDM4EGAA | |
| Hydrochloric Acid SCHEMBL4738978 | 0.81 | CACNA1B (0.46) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL14503259 | 0.78 | BACE1 (0.62) | MAPTBACE1MEN1KMT2AKDM4E | |
| SCHEMBL22279044 | 0.72 | CACNA1B (0.48) | MAPTKDM4EGAAALDH1A1ALOX15 | |
| SCHEMBL14503014 | 0.72 | GALR2 (0.61) | MAPTBACE1MEN1KMT2AGAA | |
| SCHEMBL23419098 | 0.71 | HRH3 (0.56) | MEN1KMT2AGAAMAPK1EPHX2 | |
| SCHEMBL5208161 | 0.71 | HDAC1 (0.55) | MAPTMEN1KMT2AEPHX2HTT | |
| SCHEMBL3641183 | 0.71 | CTNNB1 (0.59) | MAPTBACE1MEN1KMT2AKDM4E | |
| SCHEMBL10143797 | 0.70 | GALR2 (0.83) | BACE1LMNATP53THRBGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |