Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635500 | 0.81 | HPGD (0.90) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL22360327 | 0.80 | ADRA1A (0.61) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL17974448 | 0.78 | SMN1; SMN2 (0.62) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL28053591 | 0.77 | POLB (0.77) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL16067612 | 0.77 | POLB (0.88) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL14528664 | 0.76 | HPGD (0.65) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL14625957 | 0.76 | PTPN11 (0.57) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL16827278 | 0.76 | ADRA1A (1.00) | ADRA1ADGAT2 | |
| SCHEMBL605729 | 0.76 | POLB (1.00) | HPGDPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL29944351 | 0.75 | HPGD (1.00) | HPGDPOLBALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |