Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580152 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL27542809 | 0.92 | VCAM1 (0.62) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL29485896 | 0.85 | MAPK1 (0.64) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL29348 | 0.85 | MAPK1 (0.64) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL3497277 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL1524058 | 0.82 | MAPK1 (0.72) | ALDH1A1MAPK1TSHRVCAM1L3MBTL1 | |
| SCHEMBL11579276 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL358730 | 0.80 | MAPK1 (0.69) | ALDH1A1MAPK1TSHRVCAM1L3MBTL1 | |
| SCHEMBL13285256 | 0.80 | MAPK1 (0.42) | ALDH1A1HIF1AMAPK1TSHRVCAM1 | |
| SCHEMBL6125034 | 0.80 | MAPK1 (0.63) | ALDH1A1MAPK1TSHRVCAM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800808-A | Preparation method of 2, 4-dichloro fluorobenzene | 帕潘纳(北京)科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-112724066-B | Dihalogen impurity in ziprasidone hydrochloride intermediate and preparation method thereof | 海南鑫开源医药科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-112608303-B | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-10-26 | — | — | CN | claimed |
| CN-112724066-A | Dihalogen impurity in ziprasidone hydrochloride intermediate and preparation method thereof | 海南鑫开源医药科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112608303-A | Piperazine intermediate, preparation method and application thereof | 华南理工大学 | 2021-04-06 | — | — | CN | claimed |
| CN-104402920-B | A kind of method for synthesizing the chloroaniline of 2 halo, 3 pinacol borate 5 | 河南科技学院 | 2018-04-03 | — | — | CN | claimed |
| CN-104693036-A | Process for separating and utilizing mixing components of o-, m-, and p-nitrochlorobenzene | QINGDAO HUICHENG PETROCHEMICAL TECHNOLOGY CO LTD | 2015-06-10 | — | — | CN | claimed |
| CN-101613286-A | The separation of nitrobenzene chlorides and method of comprehensive utilization | HUAIAN IACHENG CO LTD | 2009-12-30 | — | — | CN | claimed |
| CN-101289396-A | Process for separating and utilizing mixing components of o-, m-, and p-nitrochlorobenzene | ZHEJIANG FUSHENG HOLDING GROUP (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-1357524-A | Prepn process of 2,4-dichlorofluorobenzene | KUNSHAN SHUANGHE PHARMACEUTICA (CN) | 2002-07-10 | — | — | CN | claimed |
| CN-1075949-A | The 2,4 dichloro fluorobenzene synthesis technique | NANJING MEDICINE INST (CN) | 1993-09-08 | — | — | CN | claimed |
| EP-0525019-A1 | PROCESS FOR PREPARATION OF 1,2,4-TRIFLUOROBENZENE AND 1-CHLORO-3,4-DIFLUOROBENZENE | PFIZER INC. (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0493030-A1 | Preparation of difluorobenzenes | RHONE-POULENC CHEMICALS LIMITED (GB) | 1992-07-01 | — | — | EP | claimed |
| WO-1991016287-A1 | PROCESS FOR PREPARATION OF 1,2,4-TRIFLUOROBENZENE AND 1-CHLORO-3,4-DIFLUOROBENZENE | PFIZER INC. (US) | 1991-10-31 | — | — | WO | claimed |
| WO-1991013847-A1 | PROCESS FOR PREPARING CHLORO-DIFLUOROBENZENE | ISC CHEMICALS LIMITED (GB) | 1991-09-19 | — | — | WO | claimed |
| EP-0447259-A1 | Process for preparing chloro-difluorobenzene | ISC CHEMICALS LIMITED (GB) | 1991-09-18 | — | — | EP | claimed |
| JP-1026538-A | — | — | None | — | — | JP | disclosed |
| JP-6040969-A | — | — | None | — | — | JP | disclosed |
| US-4032639-A | 2,3,4,4A-Tetrahydro-1H-pyrazino[1,2-a,]quinoxalin-5(6H)-ones and derivatives thereof for relieving hypertension | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-3989827-A | Antibacterial composition | COLGATE-PALMOLIVE COMPANY (US) | 1976-11-02 | — | — | US | disclosed |