Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083198 | 1.00 | RAB9A (0.34) | RAB9ANPC1L3MBTL1KDM4EMEN1 | |
| SCHEMBL23324992 | 0.79 | RAB9A (0.42) | RAB9ANPC1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29675203 | 0.79 | RAB9A (0.42) | RAB9ANPC1L3MBTL1KDM4EMEN1 | |
| SCHEMBL23324042 | 0.79 | ADORA2A (0.35) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL23323407 | 0.78 | RAB9A (0.42) | RAB9ANPC1L3MBTL1KDM4EMEN1 | |
| SCHEMBL29675041 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL29675166 | 0.78 | RAB9A (0.42) | RAB9ANPC1L3MBTL1KDM4EMEN1 | |
| SCHEMBL23302331 | 0.78 | RORC (0.38) | KDM4ENPSR1 | |
| SCHEMBL28777421 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL22042759 | 0.77 | MAPT (0.49) | RAB9ANPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043158-A | Fluorine-containing pyrimidine compound and process for producing the same | 优迈特株式会社 | 2023-11-10 | — | — | CN | disclosed |