Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23324992 | 1.00 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2TP53ADORA2A | |
| SCHEMBL30637693 | 0.79 | RAB9A (0.34) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL27083198 | 0.79 | RAB9A (0.34) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL30637695 | 0.78 | IMPDH2 (0.33) | LMNAPKM | |
| SCHEMBL23324042 | 0.78 | ADORA2A (0.35) | RAB9ANPC1SMN1; SMN2TP53ADORA2A | |
| SCHEMBL27083155 | 0.78 | IMPDH2 (0.33) | LMNAPKM | |
| SCHEMBL23323407 | 0.77 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL23302428 | 0.77 | NPC1 (0.39) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL28777421 | 0.77 | TSHR (0.31) | TSHR | |
| SCHEMBL23302331 | 0.77 | RORC (0.38) | KDM4ETSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585618-A | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |