SCHEMBL30639044

Cc1cn([C@H]2C[C@H](OP(=O)(S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cc(C)c(=O)[nH]c4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)C[C@@H]3OP(O)(=S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3O)[C@@H](COP(O)(=S)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	5/20	0.60

▸	TERT	O14746	2/20	0.56

▸	DTYMK	P23919	4/20	0.54

▸	P2RY2	P41231	2/20	0.48

▸	P2RY4	P51582	2/20	0.48

▸	P2RY6	Q15077	2/20	0.48

▸	POLB	P06746	2/20	0.47

▸	RNASEL	Q05823	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21489391	1.00	F2 (0.60)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29501178	1.00	F2 (0.60)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29624021	1.00	F2 (0.60)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29362785	0.97	TERT (0.57)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL21504636	0.97	F2 (0.64)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL21489387	0.97	F2 (0.64)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29376007	0.97	F2 (0.62)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL30369215	0.97	F2 (0.62)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29366358	0.97	F2 (0.62)	F2TERTDTYMKP2RY2P2RY4
SCHEMBL29624082	0.97	F2 (0.62)	F2TERTDTYMKP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12516087-B2	Methods and compositions comprising therapeutic gamma peptide nucleic acid-based molecules	UNIVERSITY OF IOWA RESEARCH FOUNDATION (US)	2026-01-06	—	—	US	disclosed
US-20230322862-A1	METHODS AND COMPOSITIONS COMPRISING THERAPEUTIC GAMMA PEPTIDE NUCLEIC ACID-BASED MOLECULES	UNIVERSITY OF CONNECTICUT	2023-10-12	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230322862-A1	METHODS AND COMPOSITIONS COMPRISING THERAPEUTIC GAMMA PEPTIDE NUCLEIC ACID-BASED MOLECULES	POLI, POLRMT, POLQ	F2 3878/4885TERT 605/4885DTYMK 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.