SCHEMBL29366358

SCHEMBL29366358

Cc1cn(C2CC(O)C(COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4ccc(N)nc4=O)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(O)(=S)OC3CC(n4ccc(N)nc4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(O)(=S)OC3CC(n4ccc(N)nc4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(O)(=S)OC3CC(n4ccc(N)nc4=O)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cnc5c(N)ncnc54)OC3COP(O)(=S)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 5/20 0.62
▸ DTYMK P23919 4/20 0.56
▸ TERT O14746 2/20 0.55
▸ P2RY2 P41231 2/20 0.49
▸ P2RY4 P51582 2/20 0.49
▸ P2RY6 Q15077 2/20 0.49
▸ POLB P06746 2/20 0.48
▸ RNASEL Q05823 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420169 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL30369215 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29376343 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29386416 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29376007 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29624082 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29959424 1.00 F2 (0.62) F2DTYMKTERTP2RY2P2RY4
SCHEMBL30656494 0.99 F2 (0.61) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29354146 0.98 F2 (0.60) F2DTYMKTERTP2RY2P2RY4
SCHEMBL29361881 0.98 F2 (0.60) F2DTYMKTERTP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090160-A2 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2026-04-30 — — WO claimed
EP-4701663-A1 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS, COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-03-04 — — EP claimed
EP-4554628-A1 HIV IMMUNOGENIC POLYPEPTIDES AND VACCINES AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-05-21 — — EP claimed
WO-2024222890-A1 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS, COMBINATIONS AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2024-10-31 — — WO claimed
US-20240207409-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA INC (US) 2024-06-27 — — US claimed
EP-4326329-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES Civi Biopharma, Inc. (US) 2024-02-28 — — EP claimed
WO-2024015741-A1 HIV IMMUNOGENIC POLYPEPTIDES AND VACCINES AND USES THEREOF GILEAD SCIENCES, INC. (US) 2024-01-18 — — WO claimed
EP-4204092-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2023-07-05 — — EP claimed
US-20220380761-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-12-01 — — US claimed
WO-2022226217-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-10-27 — — WO claimed
EP-3999107-A1 HIV VACCINES AND METHODS OF MAKING AND USING GILEAD SCIENCES, INC. (US) 2022-05-25 — — EP claimed
WO-2022046644-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO claimed
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 — — EP disclosed
CN-122055369-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
CN-122055373-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
US-20260130893-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-05-14 — — US disclosed
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-03-10 — — US disclosed
WO-2022046644-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed
US-20220049021-A1 FLT3L-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2022-02-17 — — US disclosed
US-11236085-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS TLR8, TLR3, TLR6 F2 4608/4885DTYMK 1307/4885TERT 4237/4885
US-20240207409-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES RNGTT, RNMT, SRRT F2 4885/4885DTYMK 437/4885TERT 3199/4885
US-20260130893-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT5, PRMT1, PRMT6 F2 4873/4885DTYMK 1296/4885TERT 216/4885
US-20220380761-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES RNGTT, RNMT, SRRT F2 4885/4885DTYMK 437/4885TERT 3199/4885
US-11236085-B2 PD-1/PD-L1 inhibitors PDCD1, CD274, PDCD1LG2 F2 3949/4885DTYMK 561/4885TERT 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback