Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.55 |
| ▸ | TDO2 | P48775 | 3/20 | 0.55 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614124 | 1.00 | IDO1 (0.55) | IDO1TDO2IDO2HSD17B10CASP1 | |
| SCHEMBL26614087 | 0.87 | IDO1 (0.50) | IDO1TDO2IDO2HSD17B10CASP1 | |
| SCHEMBL30639062 | 0.87 | IDO1 (0.50) | IDO1TDO2IDO2HSD17B10CASP1 | |
| SCHEMBL30639059 | 0.84 | APAF1 (0.53) | IDO1TDO2IDO2HSD17B10CASP1 | |
| SCHEMBL26614187 | 0.84 | APAF1 (0.53) | IDO1TDO2IDO2HSD17B10CASP1 | |
| SCHEMBL26614169 | 0.81 | TDO2 (0.58) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL26855829 | 0.79 | APAF1 (0.48) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL30639088 | 0.79 | APAF1 (0.48) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL30639109 | 0.79 | APAF1 (0.58) | IDO1TDO2IDO2HSD17B10MEN1 | |
| SCHEMBL26614173 | 0.79 | APAF1 (0.58) | IDO1TDO2IDO2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |