Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.53 |
| ▸ | TDO2 | P48775 | 13/20 | 0.53 |
| ▸ | IDO2 | Q6ZQW0 | 8/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614235 | 1.00 | IDO1 (0.53) | IDO1TDO2IDO2GRM2CA1 | |
| SCHEMBL30639111 | 0.88 | TDO2 (0.64) | IDO1TDO2IDO2GRM2CA1 | |
| SCHEMBL26614145 | 0.88 | TDO2 (0.64) | IDO1TDO2IDO2GRM2CA1 | |
| SCHEMBL26855825 | 0.88 | IDO1 (0.66) | IDO1TDO2IDO2GRM2 | |
| SCHEMBL26857744 | 0.85 | IDO1 (0.51) | IDO1TDO2IDO2GRM2KCNH2 | |
| SCHEMBL26855091 | 0.81 | APAF1 (0.46) | IDO1TDO2IDO2CA1CA2 | |
| SCHEMBL26614094 | 0.77 | IDO1 (0.85) | IDO1TDO2IDO2GRM2 | |
| SCHEMBL26856245 | 0.74 | IDO1 (0.45) | IDO1TDO2IDO2 | |
| SCHEMBL26614125 | 0.71 | IDO1 (0.46) | IDO1TDO2IDO2 | |
| SCHEMBL26614133 | 0.71 | IDO1 (0.46) | IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119487031-A | Tryptanthrin derivatives and uses thereof | 威森特生物公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |