Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 0.51 |
| ▸ | TDO2 | P48775 | 11/20 | 0.51 |
| ▸ | IDO2 | Q6ZQW0 | 6/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | TNK1 | Q13470 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855825 | 0.88 | IDO1 (0.66) | IDO1TDO2IDO2GRM2 | |
| SCHEMBL26614235 | 0.85 | IDO1 (0.53) | IDO1TDO2IDO2GRM2KCNH2 | |
| SCHEMBL30639095 | 0.85 | TDO2 (0.60) | IDO1TDO2IDO2 | |
| SCHEMBL30639092 | 0.85 | IDO1 (0.53) | IDO1TDO2IDO2GRM2KCNH2 | |
| SCHEMBL26614224 | 0.85 | TDO2 (0.60) | IDO1TDO2IDO2 | |
| SCHEMBL26855331 | 0.81 | KMT2A (0.49) | IDO1TDO2IDO2 | |
| SCHEMBL26855094 | 0.77 | CTNNB1 (0.42) | IDO1TDO2IDO2 | |
| SCHEMBL26614094 | 0.75 | IDO1 (0.85) | IDO1TDO2IDO2GRM2 | |
| SCHEMBL30639055 | 0.75 | IDO1 (0.46) | IDO1TDO2IDO2 | |
| SCHEMBL26614194 | 0.72 | IDO1 (0.41) | IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |