Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 14/20 | 0.60 |
| ▸ | IDO1 | P14902 | 14/20 | 0.60 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.60 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614224 | 1.00 | TDO2 (0.60) | TDO2IDO1IDO2CAMKK2MEN1 | |
| SCHEMBL30639064 | 0.87 | TDO2 (0.75) | TDO2IDO1IDO2CDK7CHEK1 | |
| SCHEMBL26614140 | 0.87 | TDO2 (0.75) | TDO2IDO1IDO2CDK7CHEK1 | |
| SCHEMBL26857744 | 0.85 | IDO1 (0.51) | TDO2IDO1IDO2 | |
| SCHEMBL30639055 | 0.79 | IDO1 (0.46) | TDO2IDO1IDO2 | |
| SCHEMBL26614200 | 0.78 | IDO1 (0.41) | TDO2IDO1IDO2 | |
| SCHEMBL26614194 | 0.78 | IDO1 (0.41) | TDO2IDO1IDO2 | |
| SCHEMBL18133822 | 0.76 | TDO2 (0.80) | TDO2IDO1IDO2 | |
| SCHEMBL18133826 | 0.75 | IDO1 (1.00) | TDO2IDO1IDO2MEN1KMT2A | |
| SCHEMBL26855331 | 0.75 | KMT2A (0.49) | TDO2IDO1IDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |