Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855991 | 0.87 | KMT2A (0.54) | KMT2AAPAF1IDO1MEN1MAPK1 | |
| SCHEMBL26614209 | 0.83 | APAF1 (0.63) | KMT2AAPAF1IDO1MEN1MAPK1 | |
| SCHEMBL26855091 | 0.82 | APAF1 (0.46) | KMT2AAPAF1IDO1MEN1EGFR | |
| SCHEMBL26857744 | 0.81 | IDO1 (0.51) | IDO1TDO2IDO2 | |
| SCHEMBL26855094 | 0.79 | CTNNB1 (0.42) | KMT2AAPAF1IDO1MEN1TDO2 | |
| SCHEMBL26855588 | 0.76 | POLB (0.44) | KMT2AAPAF1IDO1MEN1EGFR | |
| SCHEMBL26855338 | 0.75 | IDO1 (0.47) | KMT2AAPAF1IDO1MEN1TDO2 | |
| SCHEMBL30639055 | 0.75 | IDO1 (0.46) | IDO1TDO2IDO2 | |
| SCHEMBL30639095 | 0.75 | TDO2 (0.60) | KMT2AIDO1MEN1TDO2IDO2 | |
| SCHEMBL26614224 | 0.75 | TDO2 (0.60) | KMT2AIDO1MEN1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |